Wednesday, February 19, 2020

Can Younger People Get Parkinson’s Diseases? - Parkinson’s Diseases 6

Young onset Parkinson for people with less than 40 years old
(credit to Pinterest)

We knew that probability to get Parkinson diseases is higher for older people, usually more than 65 years old.

Can Younger People Get Parkinson’s Diseases? The answer is yes. Scientists found that about 15% of people with diseases are less than 50 years old.

It is estimated 9,000 people of those young lives in the USA. And even few percentage is kids or teenagers.

As we know that two main causes of Parkinson’s Diseases are:
- genetics
- environment factors

It is believed that multiple family members with Parkinson’s diseases contributed to young onset Parkinson’s diseases.

As mentioned at previous postpone that no cure for Parkinson’s until recently, but people may postpone the Alzheimer’s if they got early symptoms of diseases.

Some methods to delay or manage mild symptoms diseases are:
- keep working with current jobs
- physical actives
- social actives
- medications, physicians may recommend: a MAO-B inhibitor, an amantadine, a dopamine agonist and an anticholinergic drug.

Hope, Young onset Parkinson numbers may reduce in near future

You may like to read the previous posts:

Tuesday, February 4, 2020

Can Face Masks Contain Wuhan Coronavirus?

One of simple surgical face masks

Wuhan Coronavirus are spreading worldwide. The diseases transmit from infected people to healthy people in manners.

Like other airborne diseases, Coronavirus may travel in the air within droplets when infected persons:
- breathes
- sneezes
- coughs
- talks

Without containment, it is estimated that 1 sick person could infect about 1.5 to 3.5 other people.

What is effective containment to reduce transmission or infection?


N95 type respirator or face mask

It is proved that the following containment are succeed to reduce transmission:
- identifying infected persons
- isolating who infected
- tracking who contacted the infected persons

Using face mask is one methods to prevent airborne diseases to enter mouth and nose.

Two types of face masks are recommended:
- a simple surgical face mask
- N95 respirators

A simple surgical face mask is quite cheap, and easy to be found in the market. The price is less than US$ 1 per piece.

The surgical mask is effective to block big droplets, but we may inhale very small droplets from the sides of filters.

N95 respirator is able to block from 95% to 99% airborne pathogens, germs or virus. It is good for health care workers who handle Coronavirus patients (suspected or infected).
We are in the USA, Canada, Australia or Europe may no need to use any kinds of face mask or filters, since our regions have low rate infection or no infection at all.

How many persons infected by Wuhan Coronavirus in your country recently?

Saturday, January 18, 2020

Can We Get Audio Books for Free?

Lit2Go is one of audio-books websites

We may save our money by finding free stuffs that are available surrounding us (neighborhoods) or searching through internet.

The things could include digital materials or hard materials, some of them:
- certain prescription drugs
- furniture (tables and chairs)
- clothes
- digital magazines
- digital videos and films
- digital newspapers

I myself need to learn English by listening to native speakers. Traditionally, I improve my listening ability regularly through:
- watching TV, films or videos
- listening news from radios

We have plenty of choices in the digital eras. I love to get free download or free access of audio books from websites (public domains). My favorite websites are:

- Mind websites
- Loyal books
- Librivox
- Open culture
- Project Gutenberg
- Lit2Go

We may access to hundred thousands of audio books or eBook without spending any pennies.

Have you tried to find free stuffs from internet or elsewhere? Please tell us what your experience is!

Friday, January 3, 2020

Is there Relationship between Parkinson’s Diseases and Mitochondria? – Parkinson’s Diseases 5

Illustration for simple mitochondria anatomy and physiology
(credit to MEME)

Mitochondria is organelles inside the most living cells, important to the cell since its has critical functions:
- to break down the nutrient into energy, then use or store its. Thus mitochondria is a kind of cell powerhouse.
- to process cell respiration

Disorder or dead of mitochondria could lead to dead of cells, then cause problems to organs, tissues or specific cells.

It is believed that mitochondria dysfunction may relate to many diseases, include:
- Parkinson's disease
- Alzheimer's disease
- heart disease
- diabetes
- muscle weakness
- Seizure
- Huntington’s diseases
- amyotrophic lateral sclerosis


Mechanism in mitochondria dysfunction, illustration only
(credit to frontiersin.org)

From my previous posts:
- Why People Could Get Parkinson’s Diseases? - Parkinson’s Diseases 1
- How Neuron Cells Affect on Parkinson’s Diseases? - Parkinson’s Diseases 2

We may summarize that:
1) “Neurons are brain cells.”
2) One of Neuron functions is to control our physical movement and balance
3) “These brain cells may die that affect on decreasing of dopamine, consequently, lead to movement disorders such as Parkinson’s diseases.”

Then, what relationships between mitochondria, brain cells, dopamine and Parkinson’s diseases?

Brain cells are hungrier cells, they are very much depend on mitochondria as source of energy. Malfunction or dead of mitochondria, will cause dead of brain cells.

From above summary, no 3) will be happen. We may conclude that mitochondria and brain cells responsible to Parkinson’s diseases.

Monday, December 23, 2019

Can We Have Experience to Live in Snow Igloo?

A snow igloo

When I met a woman from Greenland about several years ago, first question I asked: ”did you live in an igloo? How did you feel?”

She laughed a lot. “No body live in an igloo in Greenland,” she replied my question.

Greenland is part of Denmark, hence, Greenland people have modern life as Denmark. They live in houses in a village or apartments in a city, off course with heaters.

Actually, igloos are temporary shelter when Eskimoes are hunting, especially during winter hunting. In normal condition, they live in houses.

Now, an igloo can be rent. Many countries provided igloos for tourist purposes. The cost from as cheap as U$ 10 per night to more than US$ 200 per night. 



A snow igloo at the night

Not only in Europe, we may found igloos in America as well. Some countries that provide igloos to serve tourists are following (Alexa Noel, 2018:”9 Beautiful Igloo Hotels to Check Into This Winter):

- Lapland, Finland
- Grandvalira, Andorra
- JukkasjÀrvi, Sweden
- Alta, Norway
- Kittila, Finland
- Thale, Austria
- Quebec City, Canada
- Kirkenes, Norway
- Southern Carpathians, Romania


Have you tried to live in an igloo? Where and when? 

Friday, December 13, 2019

A Little Mermaid Statue in the America and the World

The little mermaid in the California

We may know that statue of Little Mermaid was sculptured based on a fairy tale of Danish writer, Christian Andersen.

Commissioned by Carl Jacobsen (a beer company owner), then bronze statue was initiated by sculptor, Edvard Eriksen in 1909 .

The statue of 1.25 m (4.1 feet) tall and 175 kg (386 lbs) weight sizes was completed in 1913.

Copenhagen city counsel displayed the statue close to to Tivoli Garden, nearby water side of Langelinie.

Since then, copies of statues have been spread around the globe either the same or varies in terms of:
- size (tall and eight).
- materials (bronze, granite or stone)
- poses (sitting, standing or swimming)


Little Mermaid in Songkhla beach, Thailand.

We may find a little mermaid in many countries across the world, include:
- Europe (Austria, Belgium, Cyprus, England, Finland, France, Germany, Greece, Hungary, Iceland, Italy, Lithuania, Monaco, Norway, Poland, Portugal, Spain, Turkey and Switzerland).
- North America (USA, Canada)
- South America (Brazil, Argentina, Columbia etc)
- Asia (China, India, Indonesia, Thailand etc)
- Oceania (Australia and New Zealand)

In the USA, we could see the statues in the places of:
- Glendale, California
- Solvang, California
- Greenwich, Connecticut
- Kimballton, Iowa
- Greenville, Michigan
- Salt Lake City, Utah

Have you seen “little mermaid” statue? Where? In what countries?

Tuesday, December 3, 2019

Could Drink Coffee reduce risk of Parkinson’s diseases? – Parkinson’s Diseases 4

Nondrinker coffee have higher incidence rate of Parkinson’s diseases
(credit to faculty. washington)

Researchers from Hawaii observed who drinks a lot of coffee had lower incidence rate of Parkinson's diseases.

The observations on more than 8 thousand people for 30 years was divided in five categories as shown at above graph:
- Non drinkers
- drink 4 to 8 oz of coffee per day
- drink 12 to 16 oz of coffee per day
- drink 20 to 24 oz of coffee per day
- drink 28 oz or more of coffee per day

The finding showed also that other drinks did not likely to contribute to Parkinson’s diseases. The drinks which contain caffeine are:
- Chocolate
- Black tea
- Green tea
- Cola drinks
- Mountain Dew
- Dr. Pepper


A cup of black coffee (without sugar)

The question then: How drink coffee could reduce risk of Parkinson’s diseases?

Coffee contains caffeine which include in chemical members called as Xanthine. In the brain, Xanthine is equal to Adenosine.

General speaking, If Adenosine increase in the brain, then, arousal or wakefulness will be promoted.

On the opposite, if Adenosine binds to its receptor, we will feel sleepiness. It is because:
- nerve cell activities are slowing down
- oxygen are dilated (more oxygen during we are sleeping)

In respect to Parkinson’s diseases, if Adenosine block its receptor, the dopamine of neurotransmitter will increase.

Increasing of dopamine level is believed to lower risk to get Parkinson’s diseases.

Relation of dopamine and Parkinson’s diseases may be read in my previous post (How Neuron Cells Affect on Parkinson’s Diseases?

Can Younger People Get Parkinson’s Diseases? - Parkinson’s Diseases 6

Young onset Parkinson for people with less than 40 years old (credit to Pinterest) We knew that probability to get Parkinson di...